How To Stop Dupixent | Dupixent Side Effects

If you have been prescribed Dupixent (dupilumab) for conditions such as atopic dermatitis or asthma, You may be wondering how to safely stop this injectable medication Dupixent. Although Dupixent can be an effective treatment for these conditions, there are important things to keep in mind when discontinuing the drug to avoid possible side effects or worsening of your condition. When stopping Dupixent, it is important to consult your healthcare provider before making any changes to your treatment plan. Your doctor can guide you on the best way to wean off the medication and monitor your condition during this process.

More Common Side effects of Dupixent

The more common side effects of Dupixent that you may experience are: It’s important to note that not everyone will experience these side effects, and some people may have different reactions to medications. Always consult your doctor or pharmacist if you have any concerns.

Some patients reported pain, swelling, or redness during clinical trials at the injection site. Others experienced conditions like blepharitis (inflammation of the eyelids) or keratitis (inflammation of the cornea). These reactions are typically mild and should improve over time.

In some cases, Dupixent can increase the risk of developing nasal polyps, rhinosinusitis (sinus inflammation ), or other respiratory issues in people with asthma. High levels of white blood cells called eosinophils may also occur, which can indicate inflammation in the body.

Other common side effects of Dupixent include insomnia, toothache, gastritis (inflammation of the stomach lining), joint pain, and throat soreness. Some individuals may also experience esophagitis (inflammation of the esophagus) or symptoms related to herpes zoster (shingles virus).

Prurigo nodularis, nasopharyngitis (inflammation of the nasal passages), and other infections are also possible side effects of Dupixent. It’s essential to be aware of these potential side effects and to discuss them with your doctor or pharmacist if you experience any of these symptoms while taking Dupixent.

In the Side Effect Specifics section of the drug information, you can find more details about these potential side effects, including how often they occur in clinical trials. For example, infections such as those caused by the herpes virus were reported in some patients during studies.

If you are experiencing any concerning side effects while taking Dupixent, it is essential to seek medical attention promptly. Your healthcare provider can assess your symptoms and determine the best course of action to manage any adverse reactions to the drug.

Mild side effects of Dupixent

It’s essential to be aware of these potential reactions and know when to seek medical advice.

One common mild side effect of Dupixent is joint pain, which some people may experience after receiving an injection. This discomfort at the injection site can include pain and swelling, but it usually subsides quickly.
Another possible mild side effect is the risk of developing cold sores on the lips or inside the mouth. These symptoms are often caused by herpes zoster (shingles virus) and can be managed with appropriate treatment.
Throat pain or soreness may also occur as a mild side effect of Dupixent. This discomfort can be managed with over-the-counter pain relievers and soothing remedies like warm saltwater gargles.
Some individuals may experience increased white blood cells called eosinophils while taking Dupixent. While this can indicate inflammation in the body, it is typically not a cause for concern unless levels are significantly elevated.
Insomnia and toothache are other mild side effects that some people may experience while on Dupixent. These symptoms can often be managed with proper sleep hygiene practices and dental care.
Gastritis, or stomach lining inflammation, is another potential mild side effect of Dupixent. This condition can cause discomfort in the upper abdomen and may be managed with medications to reduce stomach acid and promote healing.
It’s important to note that while these side effects are considered mild, they should still be monitored closely. If you experience any concerning symptoms or if the side effects persist or worsen, it is crucial to consult with your doctor or pharmacist for proper guidance.
The Food and Drug Administration (FDA) requires drug manufacturers to provide detailed information about potential side effects in the medication’s prescribing information. This information can help healthcare providers, and patients understand what to expect while taking Dupixent and how to manage reactions effectively.

Serious side effects of Dupixent

Now, let’s discuss some of the more severe side effects that may occur while taking Dupixent. It’s crucial to be aware of these potential reactions and know when to seek immediate medical attention.

One severe side effect of Dupixent is an allergic reaction. Suppose you experience symptoms such as difficulty breathing, swelling of the face or throat, or hives after receiving an injection. In that case, it is essential to contact your doctor or call 911 right away. Allergic reactions can be life-threatening and require immediate emergency care.

In rare cases, Dupixent may cause other serious conditions, such as severe infections or inflammatory disorders. If you develop a high fever, persistent cough, unusual fatigue, or any other concerning symptoms that may indicate a disease, it is crucial to seek medical advice promptly.

FAQs

Now, let’s address some commonly asked questions about the side effects of Dupixent:

Is it possible to have side effects after stopping Dupixent, or long-term side effects?

It is possible to experience side effects after stopping Dupixent, although this is uncommon. In some cases, individuals may develop rebound symptoms or experience a return to their original condition once treatment is discontinued. Long-term side effects of Dupixent are still being studied as the drug is relatively new. Some potential concerns include effects on vision or eye conditions, vasculitis, and other inflammatory disorders. It is essential to follow your doctor’s dosing instructions carefully and communicate any concerns or changes in your condition while taking Dupixent. If you need to stop treatment, your healthcare provider may recommend tapering off the medication gradually to minimize any potential withdrawal effects on the body. Discuss all possible risks and benefits with your doctor before discontinuing Dupixent, as they can provide personalized guidance based on your case and medical history. Additionally, if you are taking other medications or corticosteroids alongside Dupixent, following your healthcare provider’s instructions is crucial to avoid any interactions or adverse effects.

Should I expect to gain weight when taking Dupixent?

Weight gain is not typically listed as a common side effect of Dupixent. However, some people may experience changes in weight while taking the medication. In clinical trials, researchers did not find a direct link between Dupixent and weight gain. It is essential to note that individuals with atopic dermatitis or eczema may have underlying factors that contribute to weight fluctuations, such as stress or changes in eating habits. If you have concerns about weight gain while on Dupixent, discussing them with your doctor is crucial. They can provide personalized advice and address any potential factors contributing to weight changes during treatment. Additionally, if you are also taking corticosteroids like prednisone alongside Dupixent, these medications may have a more significant impact on weight. Be sure to communicate any changes in your weight or concerns with your healthcare provider to determine the best course of action for managing your condition effectively.

Does Dupixent cause hair loss?

Hair loss is not typically a common side effect of Dupixent. In clinical trials, researchers found no direct link between Dupixent and hair loss. However, some reports and research suggest that some individuals with atopic dermatitis or other conditions may experience hair loss as a symptom of their underlying condition, such as alopecia areata. It is essential to discuss any concerns about hair loss with your doctor or pharmacist. They can provide more information about potential causes of hair loss and determine if it may be related to your treatment with Dupixent or another factor. If you are experiencing significant hair loss while taking Dupixent, it is crucial to seek medical advice to address any underlying issues that may be contributing to this symptom. Your doctor can guide you in managing hair loss and recommend appropriate treatment options based on your case. Communicating any changes in hair loss or concerns with your healthcare provider is essential to ensure you receive the necessary support and care for your condition.

Is fatigue a side effect of Dupixent?

Fatigue is a possible side effect of Dupixent, although it may not affect everyone who takes it. In clinical trials, some people reported experiencing fatigue as a symptom while on Dupixent. If you are feeling tired or lacking energy while taking Dupixent, discussing your concerns with your doctor is essential. They can guide you in managing fatigue and recommend improving your energy levels. Additionally, if fatigue persists or becomes severe, your healthcare provider may explore other treatment options or adjustments to your medication regimen. Communicating any questions or concerns about fatigue with your doctor or pharmacist is crucial to ensure you receive the necessary support and care for your condition. Other medications like mepolizumab (Nucala) may also be associated with fatigue, so discussing any changes in your energy levels with your healthcare provider to determine the best course of action is essential. Remember to prioritize rest, stay hydrated, and maintain a healthy lifestyle to help manage fatigue while taking Dupixent.

What side effects can I expect when using Dupixent for asthma?

When using Dupixent for asthma, some common side effects may include reactions at the injection site, pain or swelling, sore throat, and elevated levels of eosinophils (a type of white blood cell). It is essential to discuss any concerns about these side effects with your doctor or pharmacist. Be sure to review the prescribing information for Dupixent to understand potential reactions and how to manage them effectively.

Are headaches a possible side effect of using Dupixent?

Headaches are a possible side effect of using Dupixent, although not everyone may experience them. In clinical trials, some individuals reported headaches as a symptom while on Dupixent. It is essential to discuss any concerns about headaches with your doctor or pharmacist. Other medications like Fasenra (benralizumab) and Nucala (mepolizumab) used for conditions such as asthma, rhinosinusitis, and polyps may also be associated with headaches. If you have questions or concerns about headaches while taking Dupixent, communicate them with your healthcare provider for practical guidance on managing this side effect.

Is cancer one of Dupixent’s side effects?

Cancer is not listed as a side effect of Dupixent in clinical trials. However, it is essential to discuss any concerns about cancer risk with your doctor or pharmacist. Other medications like Xolair (omalizumab) used for various types of conditions may have different risks, including breast cancer and skin cancer. If you have questions or concerns about the potential risk of cancer while taking Dupixent, be sure to address them with your healthcare provider for personalized guidance and support.

Side Effect Specifics

Some more specific side effects of Dupixent

Eye-Related Side Effects

Some individuals using Dupixent may experience eye-related side effects such as pink eye, blepharitis (eyelid inflammation), keratitis (corneal inflammation), and vision changes. Symptoms may include discharge, pain, or discomfort in the eyes. Clinical trials have observed these side effects involving people with atopic dermatitis and prurigo nodularis. If you experience any ocular symptoms while on Dupixent, discuss them with your healthcare provider for appropriate management and guidance.

What you can do

You must consult your doctor for appropriate treatment if you experience ocular side effects while on Dupixent, such as pink eye, blepharitis, or keratitis. Symptoms like dry eyes, itchiness, changes in vision, eye redness, discharge, or pain should not be ignored and may require medical attention.

Joint pain

Joint pain is a potential side effect of Dupixent reported in clinical trials involving individuals with conditions like eosinophilic esophagitis, rhinosinusitis, nasal polyps, atopic dermatitis, eczema, and asthma. If you experience joint pain while on Dupixent, communicate this symptom with your healthcare provider for proper evaluation and management.

What you can do

If you are experiencing joint pain while taking Dupixent, it is essential to consult your doctor for appropriate treatment. Your healthcare provider may recommend a pain reliever or other management strategies to help alleviate discomfort. Follow their guidance and communicate any changes or concerns with them.

Eosinophilic conditions

Eosinophilic conditions are diseases or disorders characterized by high levels of eosinophils, a type of white blood cell, in the body. Examples of eosinophilic conditions that may be treated with Dupixent include asthma, pneumonia, vasculitis, and skin conditions. Symptoms of eosinophilic conditions can vary but may include:

Fever.
Swollen lymph nodes.
Growths on the skin.
Other problems related to inflammation and infection.

If you have been diagnosed with an eosinophilic condition and are considering Dupixent as a treatment option, be sure to discuss your symptoms and medical history with your healthcare provider for personalized care.

What you can do

If you experience symptoms of an eosinophilic condition while on Dupixent, it is crucial to seek medical attention promptly. Some symptoms can be life-threatening and may require immediate intervention. Contact your doctor or go to the nearest emergency room if you are experiencing severe symptoms that could indicate a medical emergency. Do not hesitate to call 911 or your local emergency number for immediate assistance in urgent situations. Prioritizing your health and safety is essential when dealing with potential complications related to eosinophilic conditions and Dupixent treatment.

Allergic reaction

Some people may experience an allergic reaction to Dupixent, a drug that has been shown in clinical trials to have potential side effects. Symptoms of an allergic reaction can include injection site reactions such as pain and swelling, as well as skin rash, itching, flushing, and swelling in areas like the skin, lips, eyelids, feet, hands, mouth, tongue, or throat. If you notice any symptoms after taking Dupixent or during treatment, it is vital to seek medical attention immediately. Allergic reactions can be severe and may impact your ability to breathe correctly. Prioritize your health and safety by contacting your doctor or seeking emergency help.

What you can do

If you experience symptoms of an allergic reaction to Dupixent, it is crucial to contact your doctor right away. Your healthcare provider can assess your symptoms and recommend the best action. If you are experiencing severe symptoms that could indicate an emergency, do not hesitate to call 911 or your local emergency number for immediate assistance. Common ways to manage symptoms of an allergic reaction include taking antihistamines or other medications as prescribed by your doctor. Prioritize your health and well-being by seeking prompt medical attention if you suspect you are having an allergic reaction to Dupixent.

Precautions for Dupixent

Before starting Dupixent treatment, discussing your health history with your doctor is essential. Certain conditions or factors may impact the drug’s effectiveness or increase the risk of side effects. Inform your healthcare provider about any infections you may have or if you have a weakened immune system, as this could affect your body’s ability to fight off infection while on Dupixent.

Additionally, be sure to inform your doctor if you have ever had a tapeworm infection, as Dupixent treatment may need to be adjusted in these cases. Your doctor can provide information on infection prevention and treatment options while on Dupixent.

When receiving Dupixent treatment, it is crucial to stay up-to-date on vaccines. Certain vaccines, such as measles, mumps, rubella, and chickenpox, may need to be administered in a different form or extra time while on Dupixent. Discuss with your doctor the best options for vaccination to protect yourself against harmful germs.

If you have a history of joint pain, inform your doctor before starting Dupixent treatment. In some cases, joint pain may be a side effect of the drug, and your doctor can provide you with treatment options to manage it effectively.

For individuals with asthma, it is essential to monitor any asthma symptoms or attacks while on Dupixent. If you experience any worsening of asthma symptoms or asthma attacks while taking Dupixent, contact your doctor immediately. Your healthcare provider can assess your symptoms and recommend the best course of action to manage your asthma effectively.

Be sure to discuss any potential allergic reactions you may have had in the past to medications or ingredients with your doctor before starting Dupixent treatment. Your doctor can help determine if Dupixent is right for you based on your medical history and available treatment options.

To stay informed and educated about Dupixent and its potential side effects. Always follow your doctor’s instructions carefully and communicate openly about any concerns or questions you may have regarding your treatment with Dupixent.

Taking these precautions and staying proactive in discussing your health history and concerns with your doctor can help ensure a safe and effective experience with Dupixent treatment. Prioritizing open communication with your healthcare provider will help you make informed decisions about your treatment plan, ultimately leading to better health outcomes. Stay vigilant about monitoring any changes in your condition while on Dupixent, and don’t hesitate to seek medical assistance if you experience any concerning symptoms or reactions.

Alcohol and Dupixent

When taking Dupixent, it is essential to avoid alcohol due to potential interactions. Your doctor may advise against alcohol consumption based on your medical conditions. It is crucial to prioritize your health and follow your doctor’s advice regarding alcohol and Dupixent. Consuming alcohol while on Dupixent may worsen certain situations, so it is best to abstain for optimal results. Always consult your healthcare provider for personalized recommendations on managing your condition while on Dupixent treatment. Remember, your doctor’s guidance is essential in ensuring the safety and effectiveness of your treatment plan.

Pregnancy and Breastfeeding while taking Dupixent

If you are pregnant or breastfeeding while taking Dupixent, it is essential to consult your doctor before continuing the medication. Your doctor can discuss the best options for you and your baby’s health. Consider participating in a pregnancy registry for Dupixent by calling 877-311-8972 or visiting the registry website for more information. It is crucial to weigh the advantages and disadvantages of continuing Dupixent while pregnant or breastfeeding. Your doctor can guide alternative feeding options for your child if needed. Prioritize open communication with your healthcare provider to ensure your and your baby’s safety and well-being during this time.

When to talk with your doctor

When taking medications like Dupixent, it is crucial to be aware of potential side effects. Suppose you experience any concerning side effects while on Dupixent; do not hesitate to contact your doctor or pharmacist for guidance. It is essential to ask questions and stay informed about the drug through research articles and information your healthcare provider provides. Before starting Dupixent:

Discuss dosage and cost with your doctor.
Be proactive in asking about potential interactions with medications you may be taking.
Look into the specific conditions that Dupixent treats, such as various skin conditions like eczema and dermatitis, asthma, and allergies.

If you need more information or support, consider contacting a dermatology or asthma and allergies hub for additional resources. Your doctor can provide insight into your condition’s most effective treatment plan while on Dupixent.

Stay informed about any updates or new research findings related to Dupixent to ensure you receive the best possible care. Always prioritize open communication with your healthcare provider to address any concerns or questions about your medication. Remember, your health and well-being are top priorities, so do not hesitate to seek guidance from medical professionals when needed.

How To Stop Dupixent | Dupixent Side Effects

More Common Side effects of Dupixent

Mild side effects of Dupixent

Serious side effects of Dupixent

FAQs

Is it possible to have side effects after stopping Dupixent, or long-term side effects?

Should I expect to gain weight when taking Dupixent?

Does Dupixent cause hair loss?

Is fatigue a side effect of Dupixent?

What side effects can I expect when using Dupixent for asthma?

Are headaches a possible side effect of using Dupixent?

Is cancer one of Dupixent’s side effects?